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Preparation of 2-bromo-6-(trifluoromethoxy)benzoic acid_Kain Industrial Additive
Background and overview[1] 2-Bromo-6-(trifluoromethoxy)benzoic acid can be used as a pharmaceutical synthesis intermediate. It can use 2-amino-6-(trifluoromethyl)benzoic acid as the starting material …
Preparation of 2-chloro-4-methylphenylboronic acid_Kain Industrial Additive
Background and overview[1] 2-Chloro-4-methylbenzeneboronic acid can be used as a pharmaceutical synthesis intermediate and is often used as a raw material for coupling reactions such as Suzuki. 2-Chlo…
Preparation of Sitagliptin Impurity 13_Kain Industrial Additive
Background and overview[1] Sitagliptin, chemical name (2R)-4-oxo-4-[3-trifluoromethyl-5,6-dihydro[1,2,4]triazole[4 , 3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)-butan-2-amine, which is a dipeptide…
Preparation of 2-fluoro-4-iodoaniline_Kain Industrial Additive
Background and Overview[1] 2-Fluoro-4-iodoaniline is one of the most important intermediates in the dye industry. In the dye industry, it can be used to manufacture acid ink blue G, acid medium BS, ac…
Preparation of 3-bromo-1,3,4,5-tetrahydro-2H-1-benzazepine-2-one_Kain Industrial Additive
Background and Overview[1] 3-Bromo-1,3,4,5-tetrahydro-2H-1-benzazepine-2-one is an intermediate in the synthesis of benazepril hydrochloride. Benazepril hydrochloride is a first-line antihypertensive …
Preparation of benzene sulfonyl chloride_Kain Industrial Additive
Background and Overview[1] Benzenesulfonyl chloride is a white flake crystal with a melting point of 69-71°C. It is an important organic synthesis drug intermediate and is mainly used in the synthesis…
Preparation of m-methoxypropiophenone_Kain Industrial Additive
Background and Overview[1] Me-methoxypropiophenone is a key intermediate used in the production of the drug tapentadol. Tapentadol is a novel oral analgesic drug that acts on the central nervous syste…
Preparation of 1-(4-hydroxyphenyl)piperazine dicyanobromide_Kain Industrial Additive
Overview[1] 1-(4-hydroxyphenyl)piperazine dicyanobromide can be used as a pharmaceutical synthesis intermediate, such as the preparation of 1-acetyl-4-(4-hydroxyphenyl)piperazine, ketoconazole (Ketoco…
Preparation of 2-[(4-chlorophenyl)(4-piperidinyloxy)methyl]pyridine_Kain Industrial Additive
Background and overview[1] 2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine is the key intermediate in the synthesis of bepotastine, 2-[(4-chlorophenyl)(4- Piperidinyloxy)methyl]pyridine is then s…
Preparation of 1-(4-fluorophenyl)-2-nitroethylene_Kain Industrial Additive
Background and overview[1] 1-(4-Fluorophenyl)-2-nitroethylene belongs to nitroalkenes, which are a class of biologically active compounds that are used in antibacterial, anticancer, antitumor or as ce…
