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Preparation of 2-(2-methoxy-4-niphenyl)-3-(4-niphenyl)-5-(2,4-disulfobenzene)-2H-tetrazole monosodium salt_Kay Yin industrial additives

Background and overview[1] 2-(2-Methoxy-4-niphenyl)-3-(4-niphenyl)-5-(2,4-disulfobenzene)-2H-tetrazole monosodium salt, WST-8, referred to as WST-8, is a main component in the cell activity detection …

(2S-cis)-(+)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepine-4(5H)-one Preparation_Kain Industrial Additives

Background and overview[1] (2S-cis)-(+)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepine-4(5H) -Ketone is a key intermediate in the synthesis of diltiazem. The current route to synthesize…

Preparation and application of [1,1′-bis(diphenylphosphine)ferrocene]palladium dichloride dichloromethane complex_Kain Industrial Additive

Background and overview[1] [1,1′-bis(diphenylphosphine)ferrocene]palladium dichloride dichloromethane complex (Pd(dppf)Cl2·CH2 Cl2) is a bimetallic solvent complex formed by Pd(II) and dppf, which is …

Preparation method and application of m-chloroperoxybenzoic acid_Kain Industrial Additive

Background and overview[1-2] Metachloroperoxybenzoic acid is a commonly used oxidizing agent in organic synthesis. It can oxidize alkenes, carbonyl compounds, nitrogen-, sulfur-, phosphorus-, selenium…

2-[2-[2-Chloro-3-[(1,3-dihydro-1,3,3-trimethyl-2H-indole-2-ylidene)ethylidene]-1-cyclohexane Preparation of en-1-yl]vinyl]-1,3,3-trimethyl-3H-indole 4-methylbenzenesulfonate_Kain Industrial Additive

Background and overview[1] 2-[2-[2-Chloro-3-[(1,3-dihydro-1,3,3-trimethyl-2H-indole-2-ylidene)ethylene]-1 -Cyclohexen-1-yl]vinyl]-1,3,3-trimethyl-3H-indole 4-methylbenzenesulfonate is a cyanine dye an…

Preparation of N-[4-(sulfonamide)phenyl]acrylamide_Kain Industrial Additive

Background and overview[1-2] N-[4-(Sulfonamide)phenyl]acrylamide (ASPAA) monomer can be homopolymerized or copolymerized with other monomers to form pharmacologically active polymers that are water-so…

1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H -Preparation of ethyl pyrazolo[3,4-C]pyridine-3-carboxylate_Kain Industrial Additive

Background and overview[1] 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetra Hydro-1H-pyrazolo[3,4-C]pyridine-3-carboxylic acid ethyl ester is an intermediate for the preparati…

Preparation of 3,3-dichloro-1-(4-nitrophenyl)-2-piperidone_Kain Industrial Additive

Background and overview[1] 3,3-Dichloro-1-(4-nitrophenyl)-2-piperidone is an important pharmaceutical intermediate, for example, it can be used to prepare apixaban derivatives. Apixaban is a small mol…

Preparation and application of IR-813 p-toluene sulfonate_Kain Industrial Additive

Background and overview[1-2] IR-813 p-toluenesulfonate is a cyanine dye and an infrared absorber. There are reports in the literature that IR-813 p-toluene sulfonate can be used to prepare a positive-…

Preparation of (2R, 3S)-3-(benzoylamino)-2-hydroxyphenylpropionic acid ethyl ester_Kain Industrial Additive

Background and overview[1] (2R, 3S)-3-(Benzoylamino)-2-hydroxyphenylpropanoic acid ethyl ester is an important synthetic intermediate that can be used to synthesize the anti-cancer drug paclitaxel. Th…

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