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Preparation of (2R,4S)-5-(biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid_Kain Industrial Additive
Background and overview[1] (2R,4S)-5-(biphenyl-4-yl)-4-[(tert-butoxycarbonyl) Amino]-2-methylpentanoic acid is a key intermediate in the preparation of Sacubitril. Sacubitril and valsartan can form th…
Preparation of (5R)-3-(4-bromo-3-fluorophenyl)-5-hydroxymethyloxazolidin-2-one_Kain Industrial Additive
Background and overview[1] (5R)-3-(4-Bromo-3-fluorophenyl)-5-hydroxymethyloxazolidine- 2-Keto is an oxazolidinone compound. Oxazolidinones are a class of chemical compounds that find widespread use in…
Preparation of (S)-N-glycidyl phthalimide_Kain Industrial Additive
Background and overview[1] (S)-N-glycidyl phthalimide is also called S-glycidyl phthalimide amine. (S)-N-glycidyl phthalimide is an important intermediate for the preparation of rivaroxaban, new antib…
Preparation method of 4-aminomethylbenzoic acid methyl ester hydrochloride_Kain Industrial Additive
Background and overview[1-2] 4-Aminomethylbenzoic acid methyl ester hydrochloride is a pharmaceutical intermediate, which can be prepared from 4-aminomethylbenzoic acid through one-step esterification…
Preparation and application of 4-bromo-2-iodophenol_Kain Industrial Additive
Background and overview[1] 4-Bromo-2-iodophenol, also called 2-iodo-4-bromophenol, is an organic intermediate that can be prepared by nitration and reduction of p-bromophenol, followed by diazotizatio…
Preparation method of 1,2-methylenedioxy-4-nitrobenzene_Kain Industrial Additive
Background and overview[1] 1,2-Methylenedioxy-4-nitrobenzene is an aromatic nitro compound. Aromatic nitro compounds are widely used in production and life. In addition to its traditional applications…
Preparation of 2-cyano-4-nitro-6-bromoaniline_Kain Industrial Additive
Background and overview[1] 2-Cyano-4-nitro-6-bromoaniline is a very important disperse dye intermediate and an important raw material for the synthesis of disperse dyes such as disperse blue 183. Prep…
Preparation of 2-methoxy-4-nitrobenzaldehyde_Kain Industrial Additive
Background and overview[1-2] 2-Methoxy-4-nitrobenzaldehyde is an organic intermediate. There are two main synthesis routes for its preparation. One is prepared in three steps using the compound 4-nitr…
Application of 2-hydroxybenzoic acid monoammonium salt_Kain Industrial Additive
Background and overview[1-2] 2-Hydroxybenzoic acid monoammonium salt is also called ammonium salicylate. Ammonium salicylate is an ammonium salt of organic acid generated by the reaction of salicylic …
Preparation of 3,5-dichlorobenzoyl chloride_Kain Industrial Additive
Background and overview[1] 3,5-Dichlorobenzoyl chloride is an important pesticide, pharmaceutical, and dye intermediate. In pesticide production, pesticides can be prepared through benzoic acidificati…
