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Preparation and application of dibromoquinone_Kain Industrial Additive
Overview[1][2] Dibromoquinone is an organic intermediate that can be prepared from 1,4-dihydroxybenzene in two steps. Preparation[1] Step 1 2,5-Dibromobenzene-1,4-diol: To a suspension of 1,4-dihydrox…
The structure of phenol and its influence on properties_Kain Industrial Additives
Question: Is the oxygen hybridization of phenol SP3 or sp2? What are the number of atoms and the number of electrons involved in the large π bond formed by phenol? View 1: sp2, the number of electrons…
Preparation of 2-amino-4-[(4-fluorobenzyl)amino]-1-nitrobenzene_Kain Industrial Additive
Background and overview[1] 2-Amino-4-[(4-fluorobenzyl)amino]-1-nitrobenzene can be used as a pharmaceutical synthesis intermediate. For example, retigabine is prepared, which is an anti-epileptic drug…
Preparation of 2,6-di-tert-butyl-4-mercaptophenol_Kain Industrial Additive
Background and overview[1] 2,6-di-tert-butyl-4-mercaptophenol can be used as a pharmaceutical synthesis intermediate and can be used in laboratory research and development and chemical and pharmaceuti…
Application of 1-acetoxy-2,3,5-tribenzoyloxy-1-beta-D-ribofuranose_Kain Industrial Additive
Background and overview[1] Among chemical drugs, nucleosides and their derivatives with therapeutic effects play a very important role, and their numbers are growing rapidly. Among them, 1-acetoxy-2,3…
Application of m-chloroacetophenone_Kain Industrial Additives
Background and overview[1][2] Meta-chloroacetophenone is an organic intermediate that can be prepared from benzoyl chloride as the initial raw material and can be used to synthesize 2,3’-dichloroaceto…
Application of 1-(3-methylphenyl)piperazine dihydrochloride_Kain Industrial Additive
Overview[1] 1-(3-methylphenyl)piperazine dihydrochloride is a pharmaceutical intermediate, which is the hydrochloride form of 1-(3-methylphenyl)piperazine. It can be synthesized from 1-(3 -Methylpheny…
Application of 1-(p-hydroxyphenyl)-2-thiourea_Kain Industrial Additive
Overview[1] 1-(p-Hydroxyphenyl)-2-thiourea is a pharmaceutical intermediate that can be prepared from benzoyl chloride in three steps. Preparation[1] Add 12mmol benzoyl chloride and 20mL acetone into …
Application of 1,4,7,10-tetratert-butylperylene_Kain Industrial Additive
Overview[1] 1,4,7,10-tetratert-butylperylene (TBPe) is a highly efficient fluorescent small molecule doped dye. Co-doping TBPe with MEH-PPV can improve the luminescence performance of the device and p…
Preparation and application of 2-cyano-5-fluorobenzoic acid_Kain Industrial Additive
Overview[1] 2-Cyano-5-fluorobenzoic acid is an organic intermediate that can be prepared from 2-bromo-5-fluorobenzoic acid methyl ester in two steps. Preparation[1] Step a: Heat a mixture of 2-bromo-5…
